Product Name	GPR70
Chinese Name	G protein-coupled receptor70抗体
Alias	GPCR TAS1R1; G protein coupled receptor 70; G-protein coupled receptor 70; gm 148; gm148; GPR 70; GPR70; Krueppel related zinc finger protein 3 (HKR3 protein); Sweet taste receptor T1r; T1R1; TAS1 R1; TAS1R1; Taste receptor type 1 member 1; TR 1; TR1; TS1R1_HUMAN.
literatures	Specific References  (2)     |     SL8612R has been referenced in 2 publications. [IF=4.55] Liu, Junqiang, et al. "Milk protein synthesis is regulated by T1R1/T1R3, a G protein‐coupled taste receptor, through the mTOR pathway in the mouse mammary gland." Molecular Nutrition & Food Research (2017).  IHC-F ;  Mouse.   PubMed:28497545 [IF=2.614] Cuicui Kanget al. l‐Glutamate stimulates cholecystokinin secretion via the T1R1/T1R3 mediated PLC/TRPM5 transduction pathway. J Sci Food Agric . 2020 Oct;100(13):4818-4825.  WB ;  pig.   PubMed:32478409
Research Area	Neurobiology  Signal transduction  G protein-coupled receptor
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Horse, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	90kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human GPR70/T1R1: 441-550/841 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	GPCR TAS1R1; G protein coupled receptor 70; G-protein coupled receptor 70; gm 148; gm148; GPR 70; GPR70; Krueppel related zinc finger protein 3 (HKR3 protein); Sweet taste receptor T1r; T1R1; TAS1 R1; TAS1R1; Taste receptor type 1 member 1; TR 1; TR1; TS1R1_HUMAN. Function: Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses. Subunit: Forms heterodimers with TAS1R3. Subcellular Location: Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily. SWISS: Q7RTX1 Gene ID: 80835 Database links: Entrez Gene: 80835 Human Omim: 606225 Human SwissProt: Q7RTX1 Human Unigene: 124574 Human

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