Product Name	ox-LDL
Chinese Name	氧化低密度Lipoprotein抗体
Alias	ox-LDL; LDL (Copper oxidized); Cu2SO4 oxidized low density lipoprotein; oxidized low density lipoprotein; Low density lipoprotein; MDA oxidized LDL; MDA oxidized low density lipoprotein.
literatures	Specific References  (2)     |     SL8574R has been referenced in 2 publications. [IF=3.23] Jehle J, Hoyer FF, Schöne B, Pfeifer P, Schild K, Jenniches I, et al. (2016) Myeloid-Specific Deletion of Diacylglycerol Lipase α Inhibits Atherogenesis in ApoE-Deficient Mice. PLoS ONE 11(1): e0146267.  IHC-F ;  Mouse.   PubMed:26731274 [IF=1.58] Liu, Liang, et al. "Quercetin Alleviates High-Fat Diet-Induced Oxidized Low-Density Lipoprotein Accumulation in the Liver: Implication for Autophagy Regulation." BioMed Research International 2015 (2015).  IHC-P ;  Mouse.   PubMed:26697490
Research Area	Cardiovascular  Cell biology  immunology  Lipoprotein
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, )
Applications	ELISA=1:5000-10000 ICC=1:100  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	31kDa
Cellular localization	The cell membrane Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	Mouse Cu2+ oxidised low density lipoprotein
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood. LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearence of cholesterol from the circulation. In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36. Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described. Low-density lipoprotein oxidised with Cu2SO4. Subcellular Location: Secreted. SWISS: N/A Gene ID: N/A 氧化低密度Lipoprotein是低密度Lipoprotein(low density lipoprotein,LDL)经氧化修饰后形成的,经研究认为:OXLDL的增高与动脉粥样硬化性Cardiovascular病(Arteriosclerosis cardiovascular disease,ASCVD)的发生有密切关系。
Product Picture	HepG2 cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum, C-0005) at 37°C for 20 min; Antibody incubation with (ox-LDL) polyclonal Antibody, Unconjugated (SL8574R) 1:100, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody at 37°C for 90 minutes, DAPI (blue, C02-04002) was used to stain the cell nuclei.

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