Product Name	SNAPC3
Chinese Name	SNAPC3蛋白抗体
Alias	SNAP50; SNAPc50; Proximal sequence element-binding transcription factor subunit beta; PSE binding factor subunit beta; PTF subunit beta; PTFbeta; small nuclear RNA activating complex, polypeptide 3, 50kDa; Small nuclear RNA-activating complex polypeptide 3; SNAPc 50 kDa subunit; SNAPc subunit 3; snRNA activating protein complex 50 kDa subunit; snRNA activating protein complex subunit 3; SNPC3_HUMAN.
Research Area	Cell biology  immunology  Neurobiology  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	47kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SNAPC3: 331-411/411
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	SNAPC3 is part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. SNAPC3 binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. SNAPC3 recruits TBP and BRF2 to the U6 snRNA TATA box. Function: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box. Subunit: Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC3 interacts with SNAPC1. Subcellular Location: Nuclear Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. SWISS: Q92966 Gene ID: 6619 Database links: Entrez Gene: 6619 Human Entrez Gene: 77634 Mouse Entrez Gene: 362537 Rat Omim: 602348 Human SwissProt: Q92966 Human SwissProt: Q9D2C9 Mouse SwissProt: Q5BK68 Rat Unigene: 546299 Human Unigene: 271985 Mouse Unigene: 482328 Mouse Unigene: 204909 Rat

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