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Product Name WDR23 Chinese Name WDR23蛋白抗体 Alias DCA11_HUMAN; DCAF11; DDB1 and CUL4 associated factor 11; DDB1- and CUL4-associated factor 11; DKFZp779A1629; GL014; OTTHUMP00000164696; PRO2389; WD repeat domain 23; WD repeat-containing protein 23; WDR23. Research Area Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 62kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human WDR23: 141-220/220 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. WDR23 (WD-repeat-containing protein 23), also known as GL014 or PRO2389, is a 546 amino acid protein that contains seven WD-repeats. WDR23 is expressed as three isoforms due to alternative splicing events.
Function:
May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
Subunit:
Interacts with DDB1 and CUL4A.
Similarity:
Contains 7 WD repeats.
SWISS:
Q8TEB1
Gene ID:
80344
Database links:Entrez Gene: 80344 Human
Entrez Gene: 28199 Mouse
Omim: 613317 Human
SwissProt: Q8TEB1 Human
SwissProt: Q91VU6 Mouse
Unigene: 525251 Human
Unigene: 11535 Mouse
Unigene: 16542 Rat
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