Product Name	RAB40C
Chinese Name	RAS癌基因家族蛋白RAB40C抗体
Alias	Rar like protein; Ras like protein family member 8C; SOCS box containing protein RAR3; rab 40C; Rab40c; RAB40C, member RAS oncogene family; RAR (RAS like GTPASE) like; RAR like; Rar-like protein; RARL; RAS like GTPase; RAS like, family 8, member C; Ras related protein Rab40C; Ras-like protein family member 8C; Ras-related protein Rab-40C; RASL8C; RB40C_HUMAN; SOCS box-containing protein RAR3.
Research Area	Tumour  Cell biology  immunology  Signal transduction  G protein signal
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Cow, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	31kDa
Cellular localization	cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human RAB40C: 1-100/281
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Function: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Subunit: Component of the probable SCF-like ECS(RAB40C) E3 ubiquitin-protein ligase complex which contains CUL5, RNF7/RBX2, Elongin BC complex and RAB40C. Interacts with CUL5, RNF7, TCEB1 and TCEB2. Subcellular Location: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential). Similarity: Belongs to the small GTPase superfamily. Rab family. Contains 1 SOCS box domain. SWISS: Q96S21.1 Gene ID: 57799 Database links: UniProtKB/Swiss-Prot: Q96S21.1

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