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Product Name FRMD3 Chinese Name FRMD3蛋白抗体 Alias 4.1O; Band 4.1 like protein 4O; EPB41L4O; FERM domain containing protein 3; Ovary type protein 4.1; P410; FRMD3_HUMAN. Research Area Tumour Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 69kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human FRMD3: 301-400/597 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail FRMD3 is a multifunctional protein essential for maintaining erythrocyte shape and membrane mechanical properties. Is a putative tumor suppressor gene. 5 different isoforms generated by alternative splicing have been described.
Function:
Putative tumor suppressor gene that may be implicated in the origin and progression of lung cancer.
Subcellular Location:
Membrane; Single-pass membrane protein (Potential).
Tissue Specificity:
Ovary-specific.
Similarity:
Contains 1 FERM domain.
SWISS:
A2A2Y4
Gene ID:
257019
Database links:
Entrez Gene: 100726134 Guinea pig
Entrez Gene: 100054067 Horse
Entrez Gene: 257019 Human
Entrez Gene: 242506 Mouse
Omim: 607619 Human
SwissProt: A2A2Y4 Human
SwissProt: Q8BHD4 Mouse
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