Product Name	RMD2
Chinese Name	微管动力调节蛋白2抗体
Alias	BLOCK18; FAM82A; Fam82a1; Family with sequence similarity 82 member A; Family with sequence similarity 82, member A1; hRMD 2; hRMD 4; hRMD-2; hRMD4; MGC33318; Microtubule associated protein; PRO34163; Protein FAM82A1; PYST9371; Regulator of microtubule dynamics; Regulator of microtubule dynamics protein 2; RMD 2; RMD-2; RMD2; RMD2_HUMAN.
Research Area	Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Horse, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	65kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human FAM82A1: 301-410/410
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The second largest human chromosome, 2 consists of 237 million bases encoding over 1,400 genes and making up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes. The FAM82A gene product has been provisionally designated FAM82A pending further characterization. Subunit: Interacts with microtubules. Subcellular Location: Membrane; Single-pass membrane protein (Potential). Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=In interphase localizes in the cytoplasm, and during mitosis localizes to the spindle microtubules and spindle poles. Also detected as large dots in the perinuclear region. Similarity: Belongs to the FAM82/RMD family. SWISS: Q96LZ7 Gene ID: 151393 Database links: Entrez Gene: 151393 Human Entrez Gene: 381110 Mouse Entrez Gene: 313840 Rat Omim: 611872 Human SwissProt: Q96LZ7 Human SwissProt: Q8BSE0 Mouse SwissProt: Q498D5 Rat Unigene: 591566 Human Unigene: 293063 Mouse Unigene: 449995 Mouse Unigene: 25365 Rat

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