Product Name	FAM55D
Chinese Name	FAM55D蛋白抗体
Alias	C11orf33; Chromosome 11 open reading frame 33; FA55D_HUMAN; Fam55d; Family with sequence similarity 55 member D; Family with sequence similarity 55, member D; FLJ20127; Hypothetical protein LOC54827; Protein FAM55D.
Research Area	Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	59kDa
Cellular localization	cytoplasmic Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human FAM55D: 301-400/544
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	FAM55D is a 544 amino acid secreted protein that is expressed as two isoforms due to alternative splicing events. The gene encoding FAM55D is located on chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and ∫ thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11. The FAM55D gene product has been provisionally designated FAM55D pending further characterization. Subcellular Location: Secreted (Potential). Similarity: Belongs to the NXPE family. SWISS: Q6UWF7 Gene ID: 54827 Database links: Entrez Gene: 54827 Human Entrez Gene: 244853 Mouse Entrez Gene: 500991 Rat SwissProt: Q6UWF7 Human SwissProt: Q52KP5 Mouse SwissProt: Q5XI89 Rat Unigene: 179100 Human Unigene: 325522 Mouse Unigene: 29872 Rat

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