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Product Name CCDC88B Chinese Name 大脑亮氨酸拉链结构域蛋白抗体 Alias Brain leucine zipper domain containing protein; Brain leucine zipper domain-containing protein; Brain leucine zipper protein; BRLZ; CC88B_HUMAN; CCDC 88; CCDC 88B; Ccdc88b; Coiled coil domain containing 88; Coiled coil domain containing protein 88B; Coiled-coil domain-containing protein 88B; DKFZp434G0920; FLJ00354; FLJ37970; HkRP 3; HkRP3; Hook related protein 3; Hook-related protein 3. Research Area Cell biology immunology Neurobiology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, ) Applications ELISA=1:5000-10000 IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 79/165kDa Cellular localization The nucleus cytoplasmic Extracellular matrix Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human CCDC88B/BRLZ/HkRP3: 1271-1476/1476 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail HkRP3, also known as CCDC88B (coiled-coil domain-containing protein 88B) or BRLZ (brain leucine zipper domain-containing protein), is a 1,476 amino acid protein that belongs to the CCDC88 family. Members of the hook-related protein family are characterized by the presence of a C-terminal hook-related domain and an N-terminal potential microtubule binding domain. HkRP3 may be involved in the linkage of various organelles to microtubules, and exists as six alternatively spliced isoforms. The gene encoding HkRP3 maps to human chromosome 11q13.1 and mouse chromosome 19 A. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
Similarity:
Belongs to the CCDC88 family.
SWISS:
A6NC98
Gene ID:
283234
Database links:Entrez Gene: 283234 Human
Omim: 611205 Human
SwissProt: A6NC98 Human
Unigene: 98564 Human
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