Product Name	CCDC56
Chinese Name	卷曲螺旋结构域蛋白56抗体
Alias	CCD56_HUMAN; CCDC56; Coiled-coil domain-containing protein 56; HSPC009; COX25; COA 3; MITRAC12.
Research Area	Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	12kDa
Cellular localization	cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from Human CCDC56: 51-106/106
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC56 (coiled-coil domain containing 56) is a 106 amino acid single-pass membrane protein encoded by a gene that maps to human chromosome 17q21. Encoding over 1,200 genes, chromosome 17 comprises over 2.5% of the human genome. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Function: Putative COX assembly factor (By similarity). Subcellular Location: Mitochondrion membrane; Single-pass membrane protein (By similarity). Similarity: Belongs to the COA3 family. SWISS: Q9Y2R0 Gene ID: 28958 Database links: Entrez Gene: 28958 Human SwissProt: Q9Y2R0 Human Unigene: 16059 Human

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