Product Name	AGFG1
Chinese Name	艾滋病病毒复制Binding protein抗体
Alias	HIV 1 Rev binding protein; RAB; Rev/Rex activation domain-binding protein; RIP; AGFG1; AGFG1_HUMAN; Arf-GAP domain and FG repeats-containing protein 1; ArfGAP with FG repeats 1; HIV-1 Rev-binding protein; HRB; Nucleoporin like protein RIP; Nucleoporin-like protein RIP; Rev interacting protein; Rev-interacting protein.
Research Area	Cell biology  immunology  Signal transduction  Bacteria and viruses
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Horse, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	58kDa
Cellular localization	The nucleus cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human AGFG1: 276-380/562
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Required for vesicle docking or fusion during acrosome biogenesis (By similarity). May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication. Function: Required for vesicle docking or fusion during acrosomebiogenesis (By similarity). May play a role in RNA trafficking orlocalization. In case of infection by HIV-1, acts as a cofactor forviral Rev and promotes movement of Rev-responsiveelement-containing RNAs from the nuclear periphery to thecytoplasm. This step is essential for HIV-1 replication. Subunit: Interacts with EPS15R and EPS15. Interacts with FCHO1. Subcellular Location: Nucleus. Cytoplasmic vesicle. Tissue Specificity: Ubiquitously expressed. Post-translational modifications: O-glycosylated (By similarity). Similarity: Contains 1 Arf-GAP domain. SWISS: P52594 Gene ID: 3267 Database links: Entrez Gene: 536149 Cow Entrez Gene: 3267 Human Entrez Gene: 15463 Mouse Entrez Gene: 363266 Rat Omim: 600862 Human SwissProt: Q2TA45 Cow SwissProt: P52594 Human SwissProt: Q8K2K6 Mouse SwissProt: Q4KLH5 Rat Unigene: 352962 Human Unigene: 392569 Mouse Unigene: 433409 Mouse Unigene: 3734 Rat
Product Picture	Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti- AGFG1 (SL8072R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58kD Observed band size: 55 kD

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