Product Name	PLEKHM3
Chinese Name	血小板白细胞C激酶底物同源结构域M3抗体
Alias	DAPR; PH domain containing family M member 3; PH domain-containing family M member 3; PKHM3_HUMAN; Pleckstrin homology domain containing family M member 3; Pleckstrin homology domain-containing family M member 3; PLEKHM1L; Plekhm3.
Research Area	Cell biology  immunology  Developmental biology  Cyclin  Cell differentiation
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Horse, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	87kDa
Cellular localization	cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human PLEKHM3: 651-761/761
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	PLEKHM3 (pleckstrin homology domain containing, family M, member 3), also known as DAPR or PLEKHM1L (pleckstrin homology domain containing, family M, member 1-like), is a 761 amino acid phosphoprotein that contains two pleckstrin homology (PH) domains and one phorbol-ester/DAG-type zinc finger. Conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, PLEKHM3 exists as three alternatively spliced isoforms that participate in metal ion binding. The gene that encodes PLEKHM3 maps to human chromosome 2q33.3. As the second largest human chromosome, chromosome 2 makes up approximately 8% of the human genome and contains 237 million bases encoding over 1,400 genes. Chromosome 2 contains a probable vestigial second centromere, as well as vestigial telomeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes. Similarity: Contains 2 PH domains. Contains 1 phorbol-ester/DAG-type zinc finger. SWISS: Q6ZWE6 Gene ID: 389072 Database links: Entrez Gene: 389072 Human Entrez Gene: 241075 Mouse Entrez Gene: 316455 Rat SwissProt: Q6ZWE6 Human SwissProt: Q8BM47 Mouse Unigene: 159188 Human Unigene: 239534 Mouse

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