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Product Name PLEKHM3 Chinese Name 血小板白细胞C激酶底物同源结构域M3抗体 Alias DAPR; PH domain containing family M member 3; PH domain-containing family M member 3; PKHM3_HUMAN; Pleckstrin homology domain containing family M member 3; Pleckstrin homology domain-containing family M member 3; PLEKHM1L; Plekhm3. Research Area Cell biology immunology Developmental biology Cyclin Cell differentiation Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Horse, Rabbit, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 87kDa Cellular localization cytoplasmic The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human PLEKHM3: 651-761/761 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail PLEKHM3 (pleckstrin homology domain containing, family M, member 3), also known as DAPR or PLEKHM1L (pleckstrin homology domain containing, family M, member 1-like), is a 761 amino acid phosphoprotein that contains two pleckstrin homology (PH) domains and one phorbol-ester/DAG-type zinc finger. Conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, PLEKHM3 exists as three alternatively spliced isoforms that participate in metal ion binding. The gene that encodes PLEKHM3 maps to human chromosome 2q33.3. As the second largest human chromosome, chromosome 2 makes up approximately 8% of the human genome and contains 237 million bases encoding over 1,400 genes. Chromosome 2 contains a probable vestigial second centromere, as well as vestigial telomeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes.
Similarity:
Contains 2 PH domains.
Contains 1 phorbol-ester/DAG-type zinc finger.
SWISS:
Q6ZWE6
Gene ID:
389072
Database links:Entrez Gene: 389072 Human
Entrez Gene: 241075 Mouse
SwissProt: Q6ZWE6 Human
SwissProt: Q8BM47 Mouse
Unigene: 159188 Human
Unigene: 239534 Mouse
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