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Product Name CNKSR3 Chinese Name Ras激酶抑制因子连接增强蛋白3抗体 Alias CNKSR family member 3; Connector enhancer of kinase suppressor of ras 3; Maguin like protein; Membrane associated guanylate kinase interacting protein like 1; RP11 486M3 1; CNKR3_HUMAN. Research Area Cell biology Signal transduction G protein signal Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 62kDa Cellular localization cytoplasmic The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human CNKSR3: 241-510/555 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail CNKSR3 belongs to the CNKSR family. It contains 1 CRIC domain, 1 DUF1170 domain, 1 PDZ (DHR) domain and 1 SAM (sterile alpha motif) domain.
Function:
Probably involved in transepithelial sodium transport. Regulates aldosterone-induced and ENaC-mediated sodium transport possibly through regulation of the ERK pathway (By similarity).
Subcellular Location:
Cell Membrane and Cytoplasmic
Similarity:
Belongs to the CNKSR family.
Contains 1 CRIC domain.
Contains 1
Contains 1 PDZ (DHR) domain.
Contains 1 SAM (sterile alpha motif) domain.
SWISS:
Q6P9H4
Gene ID:
154043
Database links:Entrez Gene: 154043 Human
Entrez Gene: 215748 Mouse
SwissProt: Q6P9H4 Human
SwissProt: Q8BMA3 Mouse
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