TEL: +86 571 56623320 EMAIL: [email protected]
Product Name ITGB1BP2 Chinese Name 整合素β1Binding protein2抗体 Alias CHORDC3; Integrin beta 1 binding protein (melusin) 2; integrin beta 1 binding protein 2; ITGB1BP; MELUSIN; MGC119214; ITGB1BP2/CHORDC3; MSTP015; ITBP2_HUMAN. Research Area Cardiovascular Cell biology Cell adhesion molecule Cytoskeleton Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, Rat, (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 38kDa Cellular localization The nucleus cytoplasmic Extracellular matrix Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ITGB1BP2/CHORDC3: 25-110/347 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail CHORDC3 is a muscle-specific protein that interacts with the Integrin 1 cytoplasmic domain, in the hypertrophic response to mechanical overload.
Function:
May play a role during maturation and/or organization of muscles cells.
Subunit:
Interacts with beta-1 integrin subunit. This interaction is regulated by divalent cations, and it occurs only in absence of calcium.
Tissue Specificity:
Expressed in skeletal and cardiac muscles but not in other tissues.
Similarity:
Contains 2 CHORD domains.
Contains 1 CS domain.
SWISS:
Q9UKP3
Gene ID:
26548
Database links:Entrez Gene: 26548 Human
Entrez Gene: 26549 Mouse
Omim: 300332 Human
SwissProt: Q9UKP3 Human
SwissProt: Q9R000 Mouse
Unigene: 109999 Human
Unigene: 46232 Mouse
Product Picture Paraformaldehyde-fixed, paraffin embedded (rat skeletal muscle); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ITGB1BP2) Polyclonal Antibody, Unconjugated (SL8013R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.Paraformaldehyde-fixed, paraffin embedded (mouse heart); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ITGB1BP2) Polyclonal Antibody, Unconjugated (SL8013R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Scan Wechat Qrcode