Product Name	ACSBG2
Chinese Name	长链脂肪酸辅酶A连接酶ACSBG2抗体
Alias	ACSBG 2; Acyl CoA synthetase bubblegum family member 2; BGR; BGR like; BRGL; Bubblegum related acyl CoA synthetase 2; Bubblegum related protein; DKFZp434K1635; Long chain fatty acid CoA ligase; Long chain fatty acid CoA ligase ACSBG2; MGC111089; PRTD NY3; PRTDNY3.
Research Area	Tumour  Cell biology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse, Rat,  (predicted: Human, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	74kDa
Cellular localization	cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ACSBG2: 51-150/666
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	ACSBG2 belongs to the ATP-dependent AMP-binding enzyme family, bubblegum subfamily. ACSBG2 mediates activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. It is able to activate long-chain fatty acids. It is also able to activate very long-chain fatty acids, although the relevance of such activity is unclear in vivo. ACSBG2 has increased ability to activate oleic and linoleic acid. It may play a role in spermatogenesis. Function: Mediates activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Able to activate long-chain fatty acids. Also able to activate very long-chain fatty acids; however, the relevance of such activity is unclear in vivo. Has increased ability to activate oleic and linoleic acid. May play a role in spermatogenesis. Subunit: Belongs to the ATP-dependent AMP-binding enzyme family. Bubblegum subfamily. Subcellular Location: Cytoplasm. Membrane; Peripheral membrane protein. Tissue Specificity: Testis-specific. DISEASE: Weakly or not expressed in fetal testis. Highly expressed in adult testis and moderately in elderly testis. SWISS: Q5FVE4 Gene ID: 81616 Database links: Entrez Gene: 81616 Human SwissProt: Q5FVE4 Human
Product Picture	Blank control(blue): TM4 cells(fixed with 2% paraformaldehyde (10 min) , then permeabilized with 90% ice-cold methanol for 30 min on ice). Primary Antibody: Rabbit Anti-ACSBG2 antibody(SL8008R), Dilution: 1μg in 100 μL 1X PBS containing 0.5% BSA; Isotype Control Antibody: Rabbit IgG(orange) ,used under the same conditions ); Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA. Blank control:H9C2 cells(fixed with 2% paraformaldehyde (10 min) , then permeabilized with 90% ice-cold methanol for 30 min on ice). Primary Antibody: Rabbit Anti-ACSBG2 antibody(SL8008R), Dilution: 1μg in 100 μL 1X PBS containing 0.5% BSA; Isotype Control Antibody: Rabbit IgG(orange) ,used under the same conditions ); Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA.

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