Product Name	CEACAM16
Chinese Name	癌胚抗原相关Cell adhesion molecule16抗体
Alias	Carcinoembryonic antigen like 2; Carcinoembryonic antigen like 2 protein; Carcinoembryonic antigen related cell adhesion molecule 16; CEAL2; CEA16_HUMAN.
Research Area	Tumour  Cell biology  immunology  Cell adhesion molecule
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Pig, Cow, Horse, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	53kDa
Cellular localization	The cell membrane Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CEACAM16/CEAL2: 201-300/425
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene is a secreted glycoprotein that in mouse interacts with tectorial membrane proteins in the inner ear. The encoded adhesion protein is found in cochlear outer hair cells and appears to be important for proper hearing over an extended frequency range. Defects in this gene likely are a cause of non-syndromic autosomal dominant hearing loss. [provided by RefSeq, May 2012]. Function: May play a role in maintaining the integrity of the tectorial membrane. Subunit: Monomer. Homodimer. Tetramer. Interacts with TECTA. Subcellular Location: Secreted. Note=Localizes to the tip of cochlear outer hair cells and to the tectorial membrane (By similarity). DISEASE: Defects in CEACAM16 are the cause of deafness autosomal dominant type 4B (DFNA4B) [MIM:614614]. A form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. Similarity: Belongs to the immunoglobulin superfamily. CEA family. Contains 2 Ig-like C2-type (immunoglobulin-like) domains. SWISS: Q2WEN9 Gene ID: 388551 Database links: Entrez Gene: 388551 Human Omim: 614591 Human SwissProt: Q2WEN9 Human

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