Product Name	CCDC80
Chinese Name	卷曲螺旋结构域蛋白80抗体
Alias	DRO1; okuribin; SSG1; steroid sensitive gene 1; steroid sensitive protein 1; CCD50; CCD80_HUMAN; CCDC80; CL2; Coiled coil domain containing 80; Coiled coil domain containing protein 50; Coiled-coil domain-containing protein 80; Down regulated by oncogenes protein 1; Down-regulated by oncogenes protein 1; Nuclear envelope protein okuribin; Protein Ymer; Up-regulated in BRS-3 deficient mouse homolog; URB.
literatures	Specific References  (1)     |     SL7992R has been referenced in 1 publications. [IF=6.684] Jing Wang. et al. Coiled-Coil Domain Containing 80 Suppresses Nonylphenol-Induced Colorectal Cancer Cell Proliferation by Inhibiting the Activation of ERK1/2. Front Cell Dev Biol. 2021; 9: 759820  IHC ;  Human.   PubMed:34746152
Research Area	Tumour  Cell biology  Developmental biology  Neurobiology  Stem cells
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse, Rat,  (predicted: Human, Chicken, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	106kDa
Cellular localization	Extracellular matrix Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CCDC80: 201-300/950
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Promotes cell adhesion and matrix assembly. Tissue specificity: Expressed in dermal papilla and dermal fibroblasts (at protein level). Expressed in heart, thymus, placenta, pancreas, colon, epithelium, spleen and osteoblasts. Function: Promotes cell adhesion and matrix assembly (By similarity). Subunit: Binds to various extracellular matrix proteins (By similarity). Subcellular Location: Secreted, extracellular space, extracellular matrix (By similarity). Tissue Specificity: Expressed in dermal papilla and dermal fibroblasts (at protein level). Expressed in heart, thymus, placenta, pancreas, colon, epithelium, spleen and osteoblasts. Post-translational modifications: Phosphorylated. Similarity: Belongs to the CCDC80 family. SWISS: Q76M96 Gene ID: 151887 Database links: Entrez Gene: 151887 Human Entrez Gene: 67896 Mouse Entrez Gene: 64387 Rat SwissProt: Q76M96 Human SwissProt: Q8R2G6 Mouse SwissProt: Q6QD51 Rat Unigene: 477128 Human Unigene: 181074 Mouse Unigene: 2193 Rat
Product Picture	Paraformaldehyde-fixed, paraffin embedded (mouse stomach); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CCDC80) Polyclonal Antibody, Unconjugated (SL7992R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining. Paraformaldehyde-fixed, paraffin embedded (rat stomach); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CCDC80) Polyclonal Antibody, Unconjugated (SL7992R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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