Product Name	CCDC102B
Chinese Name	卷曲螺旋结构域蛋白102B抗体
Alias	ACY1L; aminoacylase 1-like1; AN; C102B_HUMAN; C18orf14; CCDC102B; chromosome 18 open reading frame 14; coiled-coil domain containing 102B; Coiled-coil domain-containing protein 102B; DKFZp434K1426; DKFZp686I08254; FLJ23594; HsT1731; MGC161726; MGC161728.
Research Area	Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse, Rat,  (predicted: Chicken, Dog, Pig, Cow, Horse, Sheep, )
Applications	WB=1:500-2000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	60kDa
Cellular localization	The nucleus cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human CCDC102B: 91-180/513
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	CCDC102B is a 513 amino acid protein that exists as three alternatively spliced isoforms. Widely expressed and found in multiple CNV (copy-number variant) regions, CCDC102B contains the deletion breakpoint of a maternally inherited deletion, which is 2.7 Mb in size, and maps to human chromosome 18q22.1. CCDC102B may play a role in the pathogenesis of diaphragmatic hernia, microphthalmia, colorectal carcinoma and schizophrenia. Encoding over 300 genes, chromosome 18 contains about 76 million bases. Translocation between chromosomes 18 and 14 is the most common translocation in cancers and occurs in follicular lymphomas. Niemann-Pick disease, hereditary hemorrhagic telangiectasia and erythropoietic protoporphyria are associated with chromosome 18 SWISS: Q68D86 Gene ID: 79839 Database links: Entrez Gene: 79839 Human SwissProt: Q68D86 Human Unigene: 280781 Human
Product Picture	Sample: A431 Cell (Human) Lysate at 40 ug Primary: Anti-CCDC102B (SL7986R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 60 kD Observed band size: 63 kD Sample: 293T Cell (Human) Lysate at 40 ug Primary: Anti-CCDC102B (SL7986R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 60 kD Observed band size: 63 kD Paraformaldehyde-fixed, paraffin embedded (mouse lymphoid); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CCDC102B) Polyclonal Antibody, Unconjugated (SL7986R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining. Paraformaldehyde-fixed, paraffin embedded (rat brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CCDC102B) Polyclonal Antibody, Unconjugated (SL7986R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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