Product Name	ATE1
Chinese Name	精氨酸tRNA的蛋白转移酶1抗体
Alias	Arginine tRNA protein transferase 1; Arginyl-tRNA--protein transferase 1; Arginyl-tRNA-protein transferase; Arginyltransferase 1; R transferase 1; EC 2.3.2.8; AI225793; ATE1_HUMAN.
Research Area	Cell biology  immunology  transcriptional regulatory factor
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	59kDa
Cellular localization	The nucleus cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ATE1: 71-150/518
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	ATE1, also known as arginyltransferase 1, is an enzyme that is involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. There are two named isoforms. Function: Involved in the post-translational conjugation ofarginine to the N-terminal aspartate or glutamate of a protein.This arginylation is required for degradation of the protein viathe ubiquitin pathway. Does not arginylate cysteine residues (Bysimilarity). Subunit: Monomer (Potential). Subcellular Location: Isoform ATE1-1: Nucleus (By similarity).Cytoplasm (By similarity). Isoform ATE1-2: Cytoplasm (By similarity). Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the R-transferase family. SWISS: O95260 Gene ID: 11101 Database links: Entrez Gene: 11101 Human Entrez Gene: 11907 Mouse Entrez Gene: 293526 Rat Omim: 607103 Human SwissProt: O95260 Human SwissProt: Q9Z2A5 Mouse Unigene: 632080 Human Unigene: 216321 Mouse

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