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Product Name ARMC3 (Cancer/testis antigen 81) Chinese Name Tumour/睾丸抗原81抗体 Alias Armadillo repeat containing 3; Armadillo repeat containing protein 3; ARMC 3; Beta catenin like protein; Cancer/testis antigen 81; CT81; FLJ25845; FLJ32827; KU CT 1; RP11 300B11.1; ARMC3_HUMAN. Research Area Tumour Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Dog, Pig, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 96kDa Cellular localization The nucleus Extracellular matrix Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ARMC3 (Cancer/testis antigen 81): 752-840/872 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail ARMC3 contains 12 ARM repeats. ARM (Armadillo/beta-catenin-like) domains are imperfect 45-amino acid repeats involved in protein-protein interactions. ARM domain-containing proteins, such as ARMC3, function in signal transduction, development, cell adhesion and mobility, and tumor initiation and metastasis. The specific function of ARMC3 is not yet known.
Tissue Specificity:
Isoform 2 is expressed in skeletal muscle, brain, lung, kidney, prostate and testis. Isoform 3 is mainly expressed in skeletal muscle, liver, spleen and thymus. Expressed in many cancer tissues and cell lines.
Similarity:
Contains 12 ARM repeats.
SWISS:
Q5W041
Gene ID:
219681
Database links:Entrez Gene: 219681 Human
Omim: 611226 Human
SwissProt: Q5W041 Human
Unigene: 659807 Human
Product Picture Paraformaldehyde-fixed, paraffin embedded (Mouse testis); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ARMC3 (Cancertestis antigen 81)) Polyclonal Antibody, Unconjugated (SL7969R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructions and DAB staining.
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