TEL: +86 571 56623320 EMAIL: [email protected]
Product Name ANKS1A Chinese Name 锚蛋白重复及SAM结构域蛋白1A抗体 Alias ANKS 1; ANKS 1A; ANKS1; ANKS1A; Ankyrin repeat and SAM domain containing 1; Ankyrin repeat and SAM domain containing protein 1A; Ankyrin repeat and SAM domain-containing protein 1A; Ankyrin repeat and sterile alpha motif domain containing 1A; ANS1A_HUMAN; KIAA0229; MGC42354; Odin. Research Area Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Rabbit, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 123kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ANKS1A: 944-1030/1134 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail May play a negative role in growth factor receptor signaling pathways.
Function:
Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control cell migration and neurite retraction.
Subunit:
Interacts with EPHA8; EPHA8 kinase activity-independent but stimulated by EPHA8 ubiquitination.
Subcellular Location:
Cytoplasm. Cell projection. Note=Cytoplasmic before and after growth factor treatment.
Tissue Specificity:
Widely expressed (at protein level).
Post-translational modifications:
Phosphorylated on tyrosine residues in response to EGF and PDGF.
Similarity:
Contains 6 ANK repeats.
Contains 1 PID domain.
Contains 2 SAM (sterile alpha motif) domains.
SWISS:
Q92625
Gene ID:
23294
Database links:Entrez Gene: 23294 Human
Entrez Gene: 224650 Mouse
Omim: 608994 Human
SwissProt: Q92625 Human
SwissProt: P59672 Mouse
Unigene: 656492 Human
Unigene: 32556 Mouse
Scan Wechat Qrcode