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Rabbit Anti-ANKS1A antibody
Rabbit Anti-ANKS1A antibody
ANKS 1; ANKS 1A; ANKS1; ANKS1A; Ankyrin repeat and SAM domain containing 1; Ankyrin repeat and SAM domain containing protein 1A; Ankyrin repeat and SAM domain-containing protein 1A; Ankyrin repeat and sterile alpha motif domain containing 1A; ANS1A_HUMAN;
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  • NO.:SL7966R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Horse,Rabbit,)
    Applications:ELISA IHC-P IHC-F IF
    concentration:1mg/ml
  • Goods click count:19
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Product Name ANKS1A
Chinese Name 锚蛋白重复及SAM结构域蛋白1A抗体
Alias ANKS 1; ANKS 1A; ANKS1; ANKS1A; Ankyrin repeat and SAM domain containing 1; Ankyrin repeat and SAM domain containing protein 1A; Ankyrin repeat and SAM domain-containing protein 1A; Ankyrin repeat and sterile alpha motif domain containing 1A; ANS1A_HUMAN; KIAA0229; MGC42354; Odin.  
Research Area Cell biology  immunology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Rabbit, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 123kDa
Cellular localization cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human ANKS1A: 944-1030/1134 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail May play a negative role in growth factor receptor signaling pathways.

Function:
Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control cell migration and neurite retraction.

Subunit:
Interacts with EPHA8; EPHA8 kinase activity-independent but stimulated by EPHA8 ubiquitination.

Subcellular Location:
Cytoplasm. Cell projection. Note=Cytoplasmic before and after growth factor treatment.

Tissue Specificity:
Widely expressed (at protein level).

Post-translational modifications:
Phosphorylated on tyrosine residues in response to EGF and PDGF.

Similarity:
Contains 6 ANK repeats.
Contains 1 PID domain.
Contains 2 SAM (sterile alpha motif) domains.

SWISS:
Q92625

Gene ID:
23294

Database links:

Entrez Gene: 23294 Human

Entrez Gene: 224650 Mouse

Entrez Gene: 309639 Rat

Omim: 608994 Human

SwissProt: Q92625 Human

SwissProt: P59672 Mouse

Unigene: 656492 Human

Unigene: 32556 Mouse



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