Product Name	phospho-NIFK (Thr234)
Chinese Name	磷酸化NIFK抗体
Alias	NIFK (phospho T234); NIFK (phospho Thr234); p-NIFK(T234); p-NIFK(Thr234); hNIFK; MKI67 FHA Domain Interacting Nucleolar Phosphoprotein; MKI67IP; NOPP34; Nucleolar phosphoprotein Nopp34; Nucleolar protein interacting with the FHA domain of pKI 67; pKi67; MK67I_HUMAN.
Product Type	Phosphorylated anti
Research Area	Tumour  Signal transduction  Cyclin
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	34kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthesised phosphopeptide derived from human NIFK/MKI67IP around the phosphorylation site of Thr234: GP(p-T)PV
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a protein that interacts with the forkhead-associated domain of the Ki-67 antigen. The encoded protein may bind RNA and may play a role in mitosis and cell cycle progression. Multiple pseudogenes exist on chromosomes 5, 10, 12, 15, and 19.[provided by RefSeq, Jan 2009]. Subunit: Binds to the FHA domain of MKI67; this interaction is enhanced in mitosis. Subcellular Location: Nucleus, nucleolus. Chromosome. Note=Localizes to mitotic chromosomes in conjunction with MKI67. Post-translational modifications: Sequentially phosphorylated on Thr-238, Thr-234 and Ser-230. Thr-234 is phosphorylated only when Thr-238 is phosphorylated. Likewise, phosphorylation at Ser-230 requires that Thr-234 and Thr-238 are phosphorylated. Phosphorylation enhances MKI67 binding. Similarity: Contains 1 RRM (RNA recognition motif) domain. SWISS: Q9BYG3 Gene ID: 84365 Database links: Entrez Gene: 84365 Human Entrez Gene: 67949 Mouse Omim: 611970 Human SwissProt: Q8TB66 Human SwissProt: Q9BYG3 Human SwissProt: Q91VE6 Mouse Unigene: 367842 Human Unigene: 280311 Mouse

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