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Product Name MTMR8 Chinese Name 肌管素相关蛋白8抗体 Alias C8orf9; DKFZP434K171; FLJ20126; LIP STYX; MTMR9; Myotubularin related protein 8; Myotubularin related protein 9. Research Area Cell biology Signal transduction Cyclin Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 77kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MTMR8: 261-350/704 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail MTMR8 is a myotubularin-related protein that is atypical to most other members of the myotubularin-related protein family because it has no dual-specificity phosphatase domain. The encoded protein contains a double-helical motif similar to the SET interaction domain, which is thought to have a role in the control of cell proliferation. In mouse, a protein similar to the encoded protein binds with MTMR7, and together they dephosphorylate phosphatidylinositol 3-phosphate and inositol 1,3-bisphosphate.
Function:
Phosphatase that acts on lipids with a phosphoinositol headgroup.
Subunit:
Interacts with MTMR9.
Subcellular Location:
Nucleus envelope.
Similarity:
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
Contains 1 myotubularin phosphatase domain.
SWISS:
Q96EF0
Gene ID:
55613
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