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Product Name S100 alpha 2 Chinese Name S100A2抗体 Alias S100 calcium binding protein A2; CAN19; MGC111539; Protein S 100L; Protein S-100L; Protein S100 A2; Protein S100-A2; Protein S100L; S100 A2; S100 calcium-binding protein A2; S100A2; S100L; S10A2_HUMAN. literatures Specific References (1) | SL7873R has been referenced in 1 publications.[IF=1.39] Wu et al. A retrospective, single-center cohort study on 65 patients with primary retroperitoneal liposarcoma. (2018) Oncol.Lett. 15:1799-1810 IHC-P ; Human.Research Area Tumour Cell biology Signal transduction Cyclin Binding protein Cell differentiation Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Goat, Cat, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 11kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human S100 alpha 2: 20-98/98 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene is a member of the S100family of proteins containing 2 EF-hand calcium-binding motifs.S100 proteins are localized in the cytoplasm and/or nucleus of awide range of cells, and involved in the regulation of a number ofcellular processes such as cell cycle progression anddifferentiation. S100 genes include at least 13 members which arelocated as a cluster on chromosome 1q21. This protein may have atumor suppressor function. Chromosomal rearrangements and alteredexpression of this gene have been implicated in breast cancer.
Function:
May act as a modulator against excess calciumaccumulation in normal human mammary epithelial cells. May alsoplay a role in suppressing tumor cell growth.
Subunit:
Homodimer. Interacts with FKBP4.
Tissue Specificity:
A subset of epithelial cells including normalhuman mammary epithelial cells and keratinocytes.
Similarity:
Belongs to the S-100 family
Contains 2 EF-hand domains.
SWISS:
P29034
Gene ID:
6273
Database links:
UniProtKB/Swiss-Prot: P29034.3
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