Product Name	katanin p80
Chinese Name	剑蛋白p80抗体
Alias	KAT; Katanin (80 kDa); Katanin p80 (WD repeat containing) subunit B 1; Katanin p80 subunit B 1; Katanin p80 subunit B1; Katanin p80 WD40-containing subunit B1; katnb1; KTNB1_HUMAN; OTTHUMP00000164672; p80 katanin.
Research Area	Cell biology  Neurobiology  Cyclin  Cell differentiation
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Dog, Horse, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	72kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human katanin p80: 151-250/655
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Microtubules, polymers of alpha and beta tubulin subunits,form the mitotic spindle of a dividing cell and help to organizemembranous organelles during interphase. Katanin is a heterodimerthat consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDaaccessory protein (p80 subunit B 1). The p60 subunit acts to severand disassemble microtubules, while the p80 subunit targets theenzyme to the centrosome. Katanin is a member of the AAA family ofATPases. Function: Participates in a complex which severs microtubules inan ATP-dependent manner. May act to target the enzymatic subunit ofthis complex to sites of action such as the centrosome. Microtubulesevering may promote rapid reorganization of cellular microtubulearrays and the release of microtubules from the centrosomefollowing nucleation. Microtubule release from the mitotic spindlepoles may allow depolymerization of the microtubule end proximal tothe spindle pole, leading to poleward microtubule flux and polewardmotion of chromosome. Microtubule release within the cell body ofneurons may be required for their transport into neuronal processesby microtubule-dependent motor proteins. This transport is requiredfor axonal growth (By similarity). Subunit: Interacts with PAFAH1B1 (By similarity). Interacts withKATNA1. This interaction enhances the microtubule binding andsevering activity of KATNA1 and also targets this activity to thecentrosome. Interacts with dynein, microtubules and NDEL1. Subcellular Location: Cytoplasm. Cytoplasm, cytoskeleton,centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm,cytoskeleton. Note=Predominantly cytoplasmic. Localized to theinterphase centrosome and mitotic spindle poles Similarity: Belongs to the WD repeat KATNB1 family. Contains 6 WD repeats. SWISS: Q9BVA0 Gene ID: 10300 Database links: UniProtKB/Swiss-Prot: Q9BVA0.1

Cartpieces

• 
• 9

  9Delete

• 
• 5

  5Delete

• 
• S

  SDelete

• 
• R

  RDelete

• 
• +

  +Delete

• 
• 2

  2Delete

• Delete

• Delete

• 
• 1

  1Delete

• 
• 1

  1Delete

• 
• $

  $Delete

• 
• 0

  0Delete

• 
• 4

  4Delete

• 
• $

  $Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 1

  1Delete

• 
• K

  KDelete

• 
• K

  KDelete

• 

• Delete

• 
• i

  iDelete

• 
• i

  iDelete

• Delete

• 
• 1

  1Delete

• Delete

• 
• 1

  1Delete

• 
• 1

  1Delete

• 
• 0

  0Delete

• Delete

• 
• 2

  2Delete

• 
• 1

  1Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 1

  1Delete

• 
• 1

  1Delete

• Delete

• 
• -

  -Delete

• 
• -

  -Delete

• 
• 0

  0Delete

• Delete

• 
• t

  tDelete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• 0

  0Delete

• 
• f

  fDelete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• Delete

• 
• 4

  4Delete

• 
• $

  $Delete

• Delete

• 
• 0

  0Delete

• Delete

• Delete

• Delete

• 
• R

  RDelete

• 
• 5

  5Delete

• 
• A

  ADelete

Totalgoods,subtotals:￥Checkout