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Rat IL-18 ELISA Kit is on line for Sunlong Medical
Sunlong Biotech / 2024-01-18

 IL-18, produced by macrophages, can cooperate with IL-12 to induce the expression of TNF-α, promote the occurrence of arthritis and the proliferation of synovial tissue. IL-18 stimulates the expression of iNOS, COX-2, IL-6 and other genes in articular chondrocytes, and induces the production of a large number of NO and PGE2, which participate in joint inflammation, injury and degeneration. IL-18 can induce chondrocytes to produce MMP-1, MMP-3, MMP-13 and promote the degradation of cartilage tissue. In addition, studies have confirmed that IL-18 up-regulates the expression of TNF receptor, VCAM-1 and ICAM-1 through NF-κB and PI3K pathways, thereby promoting the production of TNF-α by mononuclear cells/macrophages.

 

 

Cat NO.:
EL0043Ra
Product:
Sunlong Medical™ Rat IL-18 ELISA Kit
Storage
4℃ (unopened) for two years
Shipping Condition
4℃
Sample Type:
Serum | plasma | cell culture supernatant and other biological samples
Spike Recovery Range:
86% - 119%
Mean Spike Recovery:
1
CV of Intra plate:
3.3% - 4.8%
CV of Inter plate:
3.5% - 5.3%
NCBI_Gene:
29197
UniProtKB:
P97636

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