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Product Name UCHL5IP Chinese Name Ubiquitin羧基末端水解酶5互相作用蛋白1抗体 Alias 26S proteasome-associated UCH interacting protein 1; 26S proteasome-associated UCH37-interacting protein 1; Expressed-Xq28STS protein; HAUS augmin-like complex subunit 7; Haus7; HAUS7_HUMAN; UCH37 interacting protein 1; UCHL5 interacting protein; UCHL5-interacting protein; UCHL5IP; UIP1; X-linked protein STS1769. Research Area Cell biology Cell differentiation Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 41kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human UCHL5IP: 41-140/368 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.
Tissue specificity:Detected in spleen, thymus, testis, ovary, small intestine and colon, with highest levels of expression in testis and ovary.
Function:
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.
Subunit:
Component of the HAUS augmin-like complex. The complex interacts with the gamma-tubulin ring complex and this interaction is required for spindle assembly. Binds UCHL5.
Subcellular Location:
Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Localizes to interphase centrosomes and to mitotic spindle microtubules.
Tissue Specificity:
Detected in spleen, thymus, testis, ovary, small intestine and colon, with highest levels of expression in testis and ovary.
Similarity:
Belongs to the HAUS7 family.
SWISS:
Q99871
Gene ID:
55559
Database links:Entrez Gene: 55559 Human
Entrez Gene: 102642054 Mouse
Entrez Gene: 73738 Mouse
Omim: 300540 Human
SwissProt: Q99871 Human
SwissProt: Q8BKT8 Mouse
Unigene: 170835 Human
Unigene: 743822 Human
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