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Rabbit Anti-RCC2 antibody
Rabbit Anti-RCC2 antibody
RCC 2; RCC1 like protein TD 60; RCC2; Telophase disk protein of 60 kDa; Protein RCC2; RCC1-like protein TD-60; RCC2_HUMAN; Regulator of chromosome condensation 2; TD60.
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  • NO.:SL7768R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Rabbit,)
    Applications:WB ELISA IHC-P IHC-F IF
    concentration:1mg/ml
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Details

Product Name RCC2
Chinese Name 染色体浓缩调节蛋白2抗体
Alias RCC 2; RCC1 like protein TD 60; RCC2; Telophase disk protein of 60 kDa; Protein RCC2; RCC1-like protein TD-60; RCC2_HUMAN; Regulator of chromosome condensation 2; TD60.  
literatures
Specific References  (1)     |     SL7768R has been referenced in 1 publications.
[IF=2.634] Zhang S et al.miR-196a Promotes Proliferation and Inhibits Apoptosis of Immature Porcine Sertoli Cells.(2019) DNA Cell Biol.Jan;38(1):41-48.  WB ;  Pig.  
Research Area Cell biology  Cyclin  Cell differentiation  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Rabbit, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 56kDa
Cellular localization The nucleus cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human RCC2: 441-522/522 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Required for completion of mitosis and cytokinesis. May function as a guanine nucleotide exchange factor for the small GTPase RAC1.

Function:
Required for completion of mitosis and cytokinesis. May function as a guanine nucleotide exchange factor for the small GTPase RAC1.

Subunit:
Binds preferentially to the nucleotide-free form of RAC1. Interacts with microtubules.

Subcellular Location:
Nucleus, nucleolus. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Contains 7 RCC1 repeats.

SWISS:
Q9P258

Gene ID:
55920

Database links:
 UniProtKB/Swiss-Prot: Q9P258.2

Entrez Gene: 55920 Human

Entrez Gene: 108911 Mouse

Omim: 609587 Human

SwissProt: Q9P258 Human

SwissProt: Q8BK67 Mouse

Unigene: 380857 Human

Unigene: 253 Mouse

 



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