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Product Name RCC2 Chinese Name 染色体浓缩调节蛋白2抗体 Alias RCC 2; RCC1 like protein TD 60; RCC2; Telophase disk protein of 60 kDa; Protein RCC2; RCC1-like protein TD-60; RCC2_HUMAN; Regulator of chromosome condensation 2; TD60. literatures Specific References (1) | SL7768R has been referenced in 1 publications.[IF=2.634] Zhang S et al.miR-196a Promotes Proliferation and Inhibits Apoptosis of Immature Porcine Sertoli Cells.(2019) DNA Cell Biol.Jan;38(1):41-48. WB ; Pig.Research Area Cell biology Cyclin Cell differentiation Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Rabbit, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 56kDa Cellular localization The nucleus cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human RCC2: 441-522/522 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Required for completion of mitosis and cytokinesis. May function as a guanine nucleotide exchange factor for the small GTPase RAC1.
Function:
Required for completion of mitosis and cytokinesis. May function as a guanine nucleotide exchange factor for the small GTPase RAC1.
Subunit:
Binds preferentially to the nucleotide-free form of RAC1. Interacts with microtubules.
Subcellular Location:
Nucleus, nucleolus. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle.
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.
Similarity:
Contains 7 RCC1 repeats.
SWISS:
Q9P258
Gene ID:
55920
Database links:
UniProtKB/Swiss-Prot: Q9P258.2Entrez Gene: 55920 Human
Entrez Gene: 108911 Mouse
Omim: 609587 Human
SwissProt: Q9P258 Human
SwissProt: Q8BK67 Mouse
Unigene: 380857 Human
Unigene: 253 Mouse
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