Product Name	phospho-RACGAP1 (Ser387)
Chinese Name	磷酸化Rho GTP酶激活蛋白GAP抗体
Alias	RACGAP1 (phospho S387); p-RACGAP1(S387); p-RACGAP1(Ser387); GAP; Gap1; GTPase activating protein; HsCYK 4; HsCYK4; ID GAP; KIAA1478; MgcRacGAP; Rac GTPase activating protein 1; RACGAP 1.
Product Type	Phosphorylated anti
Research Area	Cell biology  Signal transduction  transcriptional regulatory factor  Cell differentiation
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse,  (predicted: Rat, Dog, Cow, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	71kDa
Cellular localization	The nucleus cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthesised phosphopeptide derived from human RACGAP1 around the phosphorylation site of Ser387: RI(p-S)GC
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases. Subunit: Heterotetramer of two molecules each of RACGAP1 and KIF23. Subcellular Location: Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Tissue Specificity: Highly expressed in testis, thymus and placenta. Expressed at lower levels in spleen and peripheral blood lymphocytes. In testis, expression is restricted to germ cells with the highest levels of expression found in spermatocytes. Expression is regulated in a cell cycle-dependent manner and peaks during G2/M phase. Similarity: Contains 1 phorbol-ester/DAG-type zinc finger. Contains 1 Rho-GAP domain. SWISS: Q9H0H5 Gene ID: 29127
Product Picture	Sample: Lung (Mouse) Lysate at 40 ug A431(Human) Cell Lysate at 30 ug A549(Human) Cell Lysate at 30 ug HL60(Human) Cell Lysate at 30 ug Hela(Human) Cell Lysate at 30 ug

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