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Rabbit Anti-GTSE1 antibody
Rabbit Anti-GTSE1 antibody
G2 and S phase-expressed protein 1; B99; B99 homolog; G 2 and S phase expressed 1; G two S phase expressed protein 1; GTSE 1; GTSE-1; GTSE1_HUMAN.
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  • NO.:SL7611R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Cow,Horse,Sheep,)
    Applications:ELISA IHC-P IHC-F IF
    concentration:1mg/ml
  • Goods click count:15
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Details

Product Name GTSE1
Chinese Name G2期/S期应答相关蛋白1抗体
Alias G2 and S phase-expressed protein 1; B99; B99 homolog; G 2 and S phase expressed 1; G two S phase expressed protein 1; GTSE 1; GTSE-1; GTSE1_HUMAN.  
Research Area Tumour  Cell biology  Chromatin and nuclear signals  Signal transduction  Apoptosis  Cyclin  transcriptional regulatory factor  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 77kDa
Cellular localization cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human GTSE1/G2 and S phase expressed 1: 51-150/720 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.

Function:
May be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis. Overexpression delays G2/M phase progression.

Subcellular Location:
Cytoplasm, cytoskeleton. Note=Associated with microtubules.

Post-translational modifications:
Phosphorylated in mitosis (By similarity).

SWISS:
Q9NYZ3

Gene ID:
51512

Database links:

Entrez Gene: 51512 Human

Entrez Gene: 29870 Mouse

Entrez Gene: 300126 Rat

Omim: 607477 Human

SwissProt: Q9NYZ3 Human

SwissProt: Q8R080 Mouse



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