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Product Name Cipar1/PARM-1 Chinese Name 前列腺雄激素抑制信号蛋白1抗体 Alias Alternative namesCastration induced prostatic apoptosis related protein 1; Cipar 1; Cipar-1; Prostatic androgen repressed message 1 protein; Protein PARM 1 Precursor; PARM1_HUMAN; PARM1; Cipar1; DKFZP564O0823; PARM-1; WSC4. Research Area Cell biology Apoptosis Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 30kDa Cellular localization cytoplasmic The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Cipar1: 201-310/310 <Extracellular> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Cipar1 may be involved in a survival program enabling certain prostatic cells to resist apoptosis. It is expressed in prostate and detected in other organs at low levels, these include the heart and various tissues of the urogenital tract; not detected in mammary gland.
Function:
May regulate TLP1 expression and telomerase activity, thus enabling certain prostatic cells to resist apoptosis
Subcellular Location:
Cell membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein.
Tissue Specificity:
Widely expressed with highest levels in heart, kidney and placenta.
Post-translational modifications:
Highly N-glycosylated and O-glycosylated.
Similarity:
Belongs to the PARM family.
SWISS:
Q6UWI2
Gene ID:
25849
Database links:Entrez Gene: 25849 Human
Entrez Gene: 231440 Mouse
SwissProt: Q6UWI2 Human
SwissProt: Q923D3 Mouse
Unigene: 105460 Human
Unigene: 5002 Mouse
Unigene: 127830 Rat
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