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Product Name BCL2L13 Chinese Name Bcl2样凋亡蛋白13抗体 Alias Apoptosis facilitator; Bcl 2 like 13; Bcl 2 like 13 protein; BCL2 like 13 apoptosis facilitator; BCL2 like 13; Bcl2 like 13 protein; MIL 1; MIL1; MIL1 protein; Protein Mil1; B2L13_HUMAN. Research Area Cell biology Apoptosis Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Chicken, Dog, Pig, Horse, Rabbit, ) Applications WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 53kDa Cellular localization The nucleus cytoplasmic The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human BCL2L13: 281-380/485 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Bcl rambo shares common structural characteristics with other members of the anti-apoptotic Bcl2 family members, but differs from them at its C-terminus, where a 250 amino acid sequence preceeds the membrane anchor region. It also differs from other pro-apoptotic Bcl-2 family members in that its membrane anchor C-terminus region is responsible for its apoptotic activity, not its Bcl-2 homology motifs. Bcl rambo may promote the activation of caspase-3 and apoptosis.
Function:
May promote the activation of caspase-3 and apoptosis.
Subunit:
Monomer
Subcellular Location:
Isoform 2: Mitochondrion membrane; Single-pass membrane protein (Potential). Nucleus.
Isoform 1: Nucleus
Tissue Specificity:
Ubiquitous, with the highest levels of expression in heart, placenta and pancreas.
Similarity:
Belongs to the Bcl-2 family.
SWISS:
Q9BXK5
Gene ID:
23786
Database links:Entrez Gene: 23786 Human
Entrez Gene: 94044 Mouse
SwissProt: Q9BXK5 Human
SwissProt: P59017 Mouse
Unigene: 631672 Human
Unigene: 27990 Mouse
Product Picture Sample:
Pancreas (Mouse) Lysate at 40 ug
Primary: Anti-Bcl 2 like 13 protein (SL7584R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 53 kD
Observed band size: 55 kD
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