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Rabbit Anti-ZHX2 antibody
Rabbit Anti-ZHX2 antibody
AFP regulator 1; AFR1; Alpha fetoprotein regulator 1; RAF; Regulator of AFP; Zinc finger and homeodomain protein 2; zinc fingers and homeoboxes 2; ZHX2_HUMAN.
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  • NO.:SL7581R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Rat,(predicted: Human,Mouse,Chicken,Dog,Pig,Cow,Horse,)
    Applications:WB ELISA IHC-P IHC-F IF
    concentration:1mg/ml
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Details

Product Name ZHX2
Chinese Name 甲胎蛋白调节蛋白1抗体
Alias AFP regulator 1; AFR1; Alpha fetoprotein regulator 1; RAF; Regulator of AFP; Zinc finger and homeodomain protein 2; zinc fingers and homeoboxes 2; ZHX2_HUMAN.  
Research Area Cell biology  immunology  Signal transduction  transcriptional regulatory factor  Zinc finger protein  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Rat,  (predicted: Human, Mouse, Chicken, Dog, Pig, Cow, Horse, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 92kDa
Cellular localization The nucleus 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human ZHX2: 451-550/837 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family. [provided by RefSeq, Jul 2008].[FUNCTION] Acts as a transcriptional repressor.[SUBUNIT] Forms homodimers. Also forms heterodimers with ZHX1 and ZHX3. Heterodimerization with ZHX1 is not necessary for repressor activity. Interacts with NFYA.[SUBCELLULAR LOCATION] Nucleus. [TISSUE SPECIFICITY] Ubiquitously expressed. [SIMILARITY] Belongs to the ZHX family.

Function:
Acts as a transcriptional repressor.

Subunit:
Forms homodimers. Also forms heterodimers with ZHX1 and ZHX3. Heterodimerization with ZHX1 is not necessary for repressor activity. Interacts with NFYA.

Subcellular Location:
Nucleus.

Tissue Specificity:
Ubiquitously expressed.

Similarity:
Belongs to the ZHX family.
Contains 2 C2H2-type zinc fingers.
Contains 4 homeobox DNA-binding domains.

SWISS:
Q9Y6X8

Gene ID:
22882

Database links:
 

UniProtKB/Swiss-Prot: Q9Y6X8.1

Entrez Gene: 22882 Human

Omim: 609185 Human

SwissProt: Q9Y6X8 Human

Unigene: 377090 Human

Unigene: 658443 Human

 



Product Picture
Paraformaldehyde-fixed, paraffin embedded (Rat breast); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ZHX2) Polyclonal Antibody, Unconjugated (SL7581R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (Rat thyroid); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ZHX2) Polyclonal Antibody, Unconjugated (SL7581R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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