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Rabbit Anti-Alpha 1 acid glycoprotein 2 antibody
Rabbit Anti-Alpha 1 acid glycoprotein 2 antibody
AGP 2; AGP B; AGP2; Alpha 1 acid glycoprotein type 2; OMD 2; ORM 2; Orosomucoid2; A1AG2_HUMAN.
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Details

Product Name Alpha 1 acid glycoprotein 2
Chinese Name α-1-酸性glycoprotein2抗体
Alias AGP 2; AGP B; AGP2; Alpha 1 acid glycoprotein type 2; OMD 2; ORM 2; Orosomucoid2; A1AG2_HUMAN.  
Research Area Cardiovascular  Cell biology  immunology  glycoprotein  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 22kDa
Cellular localization Secretory protein 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human Alpha 1 acid glycoprotein 2: 121-201/201 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined; however, it may be involved in aspects of immunosuppression. [provided by RefSeq, Jul 2008].

Function:
Functions as transport protein in the blood stream. Binds various hydrophobic ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability. Appears to function in modulating the activity of the immune system during the acute-phase reaction.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed by the liver and secreted in plasma.

Post-translational modifications:
N-glycosylated. N-glycan heterogeneity at Asn-33: Hex5HexNAc4 (minor), Hex6HexNAc5 (major) and dHex1Hex6HexNAc5 (minor).

Similarity:
Belongs to the calycin superfamily. Lipocalin family.

SWISS:
P19652

Gene ID:
5005

Database links:
UniProtKB/Swiss-Prot: P19652.2

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