Product Name	Serine carboxypeptidase 1
Chinese Name	丝氨酸羧肽酶1抗体
Alias	HSCP 1; HSCP1; likely homolog of rat and mouse retinoid-inducible serine carboxypeptidase; Retinoid inducible serine carboxypeptidase; Retinoid-inducible serine carboxypeptidase precursor; SCP 1; SCP1; SCPEP 1; SCPEP1; Serine carboxypeptidase 1; serine carboxypeptidase 1 precursor protein; RISC_HUMAN.
Research Area	Cardiovascular  Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	48kDa
Cellular localization	cytoplasmic Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human RISC/Serine carboxypeptidase 1: 121-320/452
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Vascular smooth muscle activation is a salient feature of several pathological conditions including atherosclerosis, hypertension, vein graft failure, restenosis, and transplant arteriopathy. Several new genes whose proteins could lead to such biological effects have been identified. One such protein is RISC. Tissue expression pattern of Retinoid-inducible serine carboxypeptidase (RISC) in human revealed that it was highly expressed in kidney and heart. Function: May be involved in vascular wall and kidney homeostasis (By similarity). Subcellular Location: Secreted (Potential). Similarity: Belongs to the peptidase S10 family. SWISS: Q9HB40 Gene ID: 59342 Database links: Entrez Gene: 59342 Human Entrez Gene: 74617 Mouse Entrez Gene: 114861 Rat SwissProt: Q9HB40 Human SwissProt: Q920A5 Mouse SwissProt: Q920A6 Rat Unigene: 514950 Human Unigene: 34126 Mouse
Product Picture	Tissue/cell: Human kidney; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-RISC/Serine carboxypeptidase 1 Polyclonal Antibody, Unconjugated(SL7542R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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