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Product Name ZNF336/GZF1 Chinese Name Zinc finger protein336抗体 Alias GDNF inducible zinc finger gene 1; GDNF inducible zinc finger protein 1; GDNF-inducible zinc finger protein 1; GZF 1; GZF1_HUMAN; HGNC:15808; ZBTB 23; ZBTB23; Zinc finger and BTB domain containing protein 23; Zinc finger and BTB domain-containing protein 23; Zinc finger protein 336; ZNF 336. Research Area transcriptional regulatory factor Zinc finger protein Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species Rat, (predicted: Human, Mouse, Chicken, Dog, Horse, Rabbit, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 80kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ZNF336: 541-640/711 Lsotype IgG Purification affinity purified by Protein A Buffer Solution Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail GZF1 (GDNF Inducible Zinc Finger Protein 1) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding and transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding.
Function:
Transcriptional repressor. Binds the GZF1 responsive element (GRE) (consensus: 5'-TGCGCN[TG][CA]TATA-3'). May be regulating VSX2/HOX10 expression.
Subcellular Location:
Nucleus.
Tissue Specificity:
Expressed in adult brain, heart, skeletal muscle, kidney and liver. Also detected in fetal brain and kidney, and at lower levels in fetal lung and liver.
Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 1 BTB (POZ) domain.
Contains 10 C2H2-type zinc fingers.
SWISS:
Q9H116
Gene ID:
64412
Database links:Entrez Gene: 64412 Human
Entrez Gene: 74533 Mouse
SwissProt: Q9H116 Human
SwissProt: Q4VBD9 Mouse
Unigene: 28921 Human
Unigene: 709462 Human
Unigene: 136913 Mouse
Unigene: 40179 Rat
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