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Product Name ELOVL2 Chinese Name 长链脂肪酸延长酶ELOVL2抗体 Alias 3 keto acyl CoA synthase ELOVL2; 3-keto acyl-CoA synthase Elovl2; Elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast) like 2; Elongation of very long chain fatty acids protein 2; ELOV2_HUMAN; ELOVL fatty acid elongase 2; Elovl2; FLJ20334; OTTHUMP00000016029; SSC2; ELOVL2. literatures Specific References (2) | SL7053R has been referenced in 2 publications.[IF=6.166] Dawoon Jeong. et al. ELOVL2: a novel tumor suppressor attenuating tamoxifen resistance in breast cancer. Am J Cancer Res. 2021; 11(6): 2568–2589 WB ; Human.[IF=3.231] Jiamei Liu. et al. Composition of Fatty Acids and Localization of SREBP1 and ELOVL2 Genes in Cauda Epididymides of Hu Sheep with Different Fertility. ANIMALS. 2022 Jan;12(23):3302 IHC ; Sheep.Research Area Cardiovascular Cell biology Signal transduction Diabetes Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Pig, Cow, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 35kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ELOVL2: 201-296/296 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA.
Function:
Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA.
Subcellular Location:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue Specificity:
Liver and testis.
Similarity:
Belongs to the ELO family.
SWISS:
Q9NXB9
Gene ID:
54898
Database links:Entrez Gene: 54898 Human
Entrez Gene: 54326 Mouse
Omim: 611814 Human
SwissProt: Q9NXB9 Human
SwissProt: Q9JLJ4 Mouse
Unigene: 656436 Human
Unigene: 2567 Mouse
Product Picture Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ELOVL2) Polyclonal Antibody, Unconjugated (SL7053R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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