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Product Name IL-4I1 Chinese Name 白细胞介素4诱导蛋白1抗体 Alias IL4I1; hFIG1; IL4 induced protein 1; IL-4 induced protein 1; Interleukin 4 induced protein 1; LAAO; FIG 1; Fig 1 protein; FIG1; Fig1 protein; hFIG 1; hFIG1; IL4-induced protein 1; Interleukin 4 induced 1; Interleukin four induced 1; Interleukin-4-induced protein 1; L amino acid oxidase; L-amino-acid oxidase; LAAO; LAO; Protein Fig 1; Protein Fig-1; Protein Fig1; OXLA_HUMAN. Research Area Cell biology Apoptosis Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, Rat, (predicted: Human, Dog, Pig, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 61kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human IL-4I1: 51-160/567 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a protein with limited similarity to L-amino acid oxidase which contains the conserved amino acids thought to be involved in catalysis and binding of flavin adenine dinucleotide (FAD) cofactor. The expression of this gene can be induced by interleukin 4 in B cells, however, expression of transcripts containing the first two exons of the upstream gene is found in other cell types. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012].
Function:
Lysosomal L-amino-acid oxidase with highest specific activity with phenylalanine. May play a role in lysosomal antigen processing and presentation (By similarity).
Subcellular Location:
Isoform 1: Lysosome (By similarity).
Isoform 2: Lysosome (By similarity).
Tissue Specificity:
Isoform 1 is primarily found in immune tissues.
Similarity:
Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
SWISS:
Q96RQ9
Gene ID:
259307
Database links:Entrez Gene: 259307 Human
Entrez Gene: 14204 Mouse
Omim: 609742 Human
SwissProt: Q1WMJ3 Human
SwissProt: Q96RQ9 Human
SwissProt: O09046 Mouse
Unigene: 27567 Mouse
Product Picture Paraformaldehyde-fixed, paraffin embedded (rat spleen); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (IL-4I1) Polyclonal Antibody, Unconjugated (SL6841R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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