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Product Name GAS2L1 Chinese Name 生长停滞特异性蛋白2家族1抗体 Alias GA2L1_HUMAN; GAR 22; GAR22; GAS2 like protein 1; GAS2 related protein on chromosome 22; GAS2-like protein 1; GAS2-related protein on chromosome 22; GAS2L1; Growth arrest specific 2 like 1; Growth arrest specific protein 2 like 1; Growth arrest-specific protein 2-like 1; MGC17243. Research Area Signal transduction Apoptosis Cytoskeleton Immunogen Species Rabbit Clonality Polyclonal React Species Rat, (predicted: Human, Mouse, Dog, Pig, Cow, Horse, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 73kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from Human GAS2L1: 201-300/681 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene, a member of the GAS2 family, is similar in sequence to the mouse protein Gas2, an actin-associated protein expressed at high levels in growth-arrested cells. Expression of the mouse Gas2 gene is negatively regulated by serum and growth factors. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Function:
Seems to be involved in the cross-linking of microtubules and microfilaments.
Subcellular Location:
Cytoplasm, cytoskeleton (Probable).
Similarity:
Belongs to the GAS2 family.
Contains 1 CH (calponin-homology) domain.
Contains 1 GAR domain.
SWISS:
Q99501
Gene ID:
10634
Database links:
Entrez Gene: 10634 Human
Entrez Gene: 78926 Mouse
Omim: 602128 Human
SwissProt: Q99501 Human
SwissProt: Q8JZP9 Mouse
Unigene: 322852 Human
Unigene: 374836 Mouse
Unigene: 44591 Mouse
Unigene: 22169 Rat
Product Picture Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (GAS2L1) Polyclonal Antibody, Unconjugated (SL6836R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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