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Product Name TCERG1 Chinese Name 转录延伸调节蛋白1抗体 Alias CA 150; Co activator of 150 kDa; Coactivator of 150 kDa; MGC133200; TAF 2S; TAF2S; TATA box binding protein (TBP) associated factor RNA polymerase II S 150kD; TATA box binding protein associated factor 2S; TATA box binding protein associated factor RNA polymerase II S 150kD; TCERG 1; TCERG1; Transcription elongation regulator 1; Transcription factor CA 150; Transcription factor CA150; TCRG1_HUMAN. Research Area Tumour transcriptional regulatory factor TumourCell biologyMaker Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 124kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human TCERG1/CA150: 701-800/1098 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail CA150 is a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. It interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain.
Function:
Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter.
Subunit:
Binds formin (By similarity). Binds RNA polymerase II, HD and SF1.
Subcellular Location:
Nucleus.
Tissue Specificity:
Detected in brain neurons.
Similarity:
Contains 6 FF domains.
SWISS:
O14776
Gene ID:
10915
Database links:Entrez Gene: 10915 Human
Entrez Gene: 56070 Mouse
Omim: 605409 Human
SwissProt: O14776 Human
SwissProt: Q8CGF7 Mouse
Unigene: 443465 Human
Unigene: 723884 Human
Unigene: 270511 Mouse
Product Picture Sample:
Testis(Mouse) Lysate at 40 ug
Primary: Anti-TCERG1 (SL6801R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 124 kD
Observed band size: 124kD
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