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Product Name AIFM3 Chinese Name 凋亡诱导因子3抗体 Alias AIFL; Aifm3; AIFM3_HUMAN; Apoptosis inducing factor 3; Apoptosis inducing factor like; Apoptosis inducing factor like protein; Apoptosis inducing factor, mitochondrion associated; Apoptosis-inducing factor 3; Apoptosis-inducing factor-like protein; FLJ30473; FLJ45137. Research Area Cell biology Apoptosis Mitochondrion Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Cow, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 67kDa Cellular localization cytoplasmic Mitochondrion Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human AIFM3: 21-120/605 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.
Function:
Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.
Subcellular Location:
Mitochondrion. Note=Does not translocate to the nucleus upon induction of apoptosis.
Tissue Specificity:
Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).
Similarity:
Belongs to the FAD-dependent oxidoreductase family.
Contains 1 Rieske domain.
SWISS:
Q96NN9
Gene ID:
150209
Database links:Entrez Gene: 150209 Human
Entrez Gene: 72168 Mouse
SwissProt: Q96NN9 Human
SwissProt: Q3TY86 Mouse
Unigene: 723246 Human
Unigene: 40038 Mouse
Unigene: 138718 Rat
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