Product Name	THRSP
Chinese Name	甲状腺激素反应蛋白抗体
Alias	Lpgp; LPGP1; S14; S14 protein; SPOT 14; Spot 14 protein; SPOT14; SPOT14 homolog; Thrsp; THRSP_HUMAN; Thyroid hormone inducible hepatic protein; Thyroid hormone responsive (SPOT14 homolog rat); Thyroid hormone responsive; Thyroid hormone responsive protein; Thyroid hormone responsive SPOT14; Thyroid hormone-inducible hepatic protein.
Research Area	Tumour  Cell biology  Signal transduction  TumourCell biologyMaker
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Rat,  (predicted: Human, Mouse, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	17kDa
Cellular localization	The nucleus cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human THRSP: 116-145/146
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA (By similarity). May function as transcriptional coactivator. May modulate the transcription factor activity of THRB.Mainly expressed in tissues that synthesize triglycerides. Function: Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA (By similarity). May function as transcriptional coactivator. May modulate the transcription factor activity of THRB. Subunit: Homodimer. Heterodimer with MID1IP1. Interacts with THRB and PLAGL1. Subcellular Location: Cytoplasm.Nucleus. Tissue Specificity: Mainly expressed in tissues that synthesize triglycerides. Similarity: Mainly expressed in tissues that synthesize triglycerides. Belongs to the SPOT14 family. SWISS: Q92748 Gene ID: 7069 Database links: Entrez Gene: 7069 Human Entrez Gene: 21835 Mouse Entrez Gene: 25357 Rat Omim: 601926 Human SwissProt: Q92748 Human SwissProt: Q62264 Mouse SwissProt: P04143 Rat Unigene: 591969 Human Unigene: 28585 Mouse Unigene: 81140 Rat
Product Picture	Paraformaldehyde-fixed, paraffin embedded (Rat liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (THRSP) Polyclonal Antibody, Unconjugated (SL6738R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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