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Rabbit Anti-SVH antibody
Rabbit Anti-SVH antibody
Armadillo repeat containing 10; Armadillo repeat containing protein 10; ARMC 10; ARMC10; PNAS112; Specific splicing variant involved in hepatocarcinogenesis; Splicing variant involved in hepatocarcinogenesis protein; SVH; ARM10_HUMAN.
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  • NO.:SL6737R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Mouse,(predicted: Human,Rat,Dog,Pig,Cow,Rabbit,)
    Applications:WB ELISA
    concentration:1mg/ml
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Details

Product Name SVH
Chinese Name 肝癌蛋白剪接变异体蛋白抗体
Alias Armadillo repeat containing 10; Armadillo repeat containing protein 10; ARMC 10; ARMC10; PNAS112; Specific splicing variant involved in hepatocarcinogenesis; Splicing variant involved in hepatocarcinogenesis protein; SVH; ARM10_HUMAN.  
Research Area Tumour  Cell biology  Signal transduction  Cyclin  Cell type markers  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Rabbit, )
Applications WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 38kDa
Cellular localization cytoplasmic The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human SVH/ARMC10: 131-240/343 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail SVH may play a role in cell survival and cell growth and may suppress the transcriptional activity of p53/TP53. Cellular localization Endoplasmic; reticulum membrane; Single-pass membrane protein.

Function:
May play a role in cell survival and cell growth. May suppress the transcriptional activity of p53/TP53.

Subunit:
Interacts with the DNA-binding domain of p53/TP53.

Subcellular Location:
Endoplasmic reticulum membrane; Single-pass membrane protein.

Tissue Specificity:
Expressed in all tissues tested with higher expression in placenta, liver, kidney, heart and brain.

Similarity:
Contains 1 ARM repeat.

SWISS:
Q8N2F6

Gene ID:
83787

Database links:

Entrez Gene: 83787 Human

Entrez Gene: 67211 Mouse

Entrez Gene: 296758 Rat

Omim: 611864 Human

SwissProt: Q8N2F6 Human

SwissProt: Q9D0L7 Mouse

SwissProt: B1WBW4 Rat

Unigene: 287412 Human

Unigene: 260782 Mouse

Unigene: 2408 Rat



Product Picture
Sample:
Cerebrum (Mouse) Lysate at 40 ug
Kidney (Mouse) Lysate at 40 ug
Primary: Anti-SVH (SL6737R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 53 kD
Observed band size: 53 kD

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