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Product Name SVH Chinese Name 肝癌蛋白剪接变异体蛋白抗体 Alias Armadillo repeat containing 10; Armadillo repeat containing protein 10; ARMC 10; ARMC10; PNAS112; Specific splicing variant involved in hepatocarcinogenesis; Splicing variant involved in hepatocarcinogenesis protein; SVH; ARM10_HUMAN. Research Area Tumour Cell biology Signal transduction Cyclin Cell type markers Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Dog, Pig, Cow, Rabbit, ) Applications WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 38kDa Cellular localization cytoplasmic The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SVH/ARMC10: 131-240/343 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail SVH may play a role in cell survival and cell growth and may suppress the transcriptional activity of p53/TP53. Cellular localization Endoplasmic; reticulum membrane; Single-pass membrane protein.
Function:
May play a role in cell survival and cell growth. May suppress the transcriptional activity of p53/TP53.
Subunit:
Interacts with the DNA-binding domain of p53/TP53.
Subcellular Location:
Endoplasmic reticulum membrane; Single-pass membrane protein.
Tissue Specificity:
Expressed in all tissues tested with higher expression in placenta, liver, kidney, heart and brain.
Similarity:
Contains 1 ARM repeat.
SWISS:
Q8N2F6
Gene ID:
83787
Database links:Entrez Gene: 83787 Human
Entrez Gene: 67211 Mouse
Omim: 611864 Human
SwissProt: Q8N2F6 Human
SwissProt: Q9D0L7 Mouse
Unigene: 287412 Human
Unigene: 260782 Mouse
Unigene: 2408 Rat
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