Product Name	SOX11
Chinese Name	转录因子SOX-11蛋白抗体
Alias	SRY (sex determining region Y) box 11; SRY related HMG box gene 11; Transcription factor SOX-11; SOX11_HUMAN.
Research Area	Tumour  Cell biology  Neurobiology  Signal transduction  Stem cells  transcriptional regulatory factor  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Rat,  (predicted: Mouse, Pig, Cow, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	47kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SOX11: 51-150/441
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis. [provided by RefSeq, Jul 2008] Function: Transcriptional activator. Subcellular Location: Nucleus. Tissue Specificity: Mainly expressed in the developing central nervous system. Similarity: Contains 1 HMG box DNA-binding domain. SWISS: P35716 Gene ID: 6664 Database links: Entrez Gene: 6664 Human Entrez Gene: 20666 Mouse Entrez Gene: 84046 Rat Omim: 600898 Human SwissProt: P35716 Human SwissProt: Q7M6Y2 Mouse SwissProt: P0C1G9 Rat Unigene: 432638 Human Unigene: 41702 Mouse Unigene: 466344 Mouse Unigene: 162854 Rat
Product Picture	Sample: Brain (Rat) Lysate at 40 ug Primary: Anti-SOX11 (SL6736R) at 1/300 dilution Secondary: HRP conjugated Goat-Anti-rabbit IgG (SL0295G-HRP) at 1/5000 dilution Predicted band size: 47 kD Observed band size: 47 kD Paraformaldehyde-fixed, paraffin embedded (Human breast carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SOX11) Polyclonal Antibody, Unconjugated (SL6736R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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