Product Name	VMAT1
Chinese Name	嗜铬颗粒胺TransporterVMAT1抗体
Alias	Adrenal chromaffin granule amine transporter; CGAT; CGAT; Chromaffin granule amine transporter; SLC18A1; Solute carrier family 18 (vesicular monoamine), member 1; Solute carrier family 18 member 1; VAT 1; VAT1; Vesicular amine transporter 1; VMAT 1; VMAT1_HUMAN.
Research Area	Neurobiology  Signal transduction  Transporter
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse, Rat,  (predicted: Human, Chicken, Dog, Pig, Cow, Horse, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	58kDa
Cellular localization	cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human VMAT1: 421-525/525
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 [PubMed 7905859]). See also SLC18A2 (MIM 193001).[supplied by OMIM, Mar 2008]. Function: Involved in the vesicular transport of biogenic amines. Subcellular Location: Cytoplasmic vesicle membrane; Multi-pass membrane protein. Similarity: Belongs to the major facilitator superfamily. Vesicular transporter family. SWISS: Q99536 Gene ID: 10493 Database links: Entrez Gene: 10493 Human Entrez Gene: 26949 Mouse Omim: 604631 Human SwissProt: Q99536 Human SwissProt: Q62465 Mouse Unigene: 514199 Human Unigene: 29210 Mouse
Product Picture	Sample: Lane 1: Adrenal gland (Mouse) Lysate at 40 ug Lane 2: Adrenal gland (Rat) Lysate at 40 ug Primary: Anti-VMAT1 (SL6677R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 42 kD Observed band size: 42 kD

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