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Rabbit Anti-Neurotensin antibody
Rabbit Anti-Neurotensin antibody
Human proneurotensin; NT; NT/N; NTRH; NTS1; Proneuromedin N mRNA; NEUT_HUMAN;Large neuromedin N; Neuromedin N preproprotein; NMN 125; NMN-125; NN; Tail peptide; NN; Neurotensin/neuromedin N.
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  • NO.:SL6631R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Human,Rat,(predicted: Mouse,Dog,Pig,Cow,Rabbit,)
    Applications:ELISA IHC-P IHC-F IF
    concentration:1mg/ml
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Details

Product Name Neurotensin
Chinese Name 神经紧张素抗体
Alias Human proneurotensin; NT; NT/N; NTRH; NTS1; Proneuromedin N mRNA; NEUT_HUMAN;  Large neuromedin N; Neuromedin N preproprotein; NMN 125; NMN-125; NN; Tail peptide; NN; Neurotensin/neuromedin N.
literatures
Specific References  (1)     |     SL6631R has been referenced in 1 publications.
[IF=1.64] SAKUMOTO, Ryosuke, et al. "Comparison of the global gene expression profiles in the bovine endometrium between summer and autumn." Journal of Reproduction and Development 0 (2015).  IHC-P ;  Bovine.  
Research Area Cell biology  Neurobiology  Signal transduction  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human, Rat,  (predicted: Mouse, Dog, Pig, Cow, Rabbit, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 19kDa
Cellular localization cytoplasmic Secretory protein 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human Neurotensin: 101-170/170 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active. [provided by RefSeq, Jul 2008].
Cellular localization: Secreted. Cytoplasmic vesicle > secretory vesicle. Packaged within secretory vesicles.

Function:
Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.

Subcellular Location:
Secreted. Cytoplasmic vesicle, secretory vesicle. Note=Packaged within secretory vesicles.

Similarity:
Belongs to the neurotensin family.

SWISS:
P30990

Gene ID:
4922

Database links:

Entrez Gene: 4922 Human

Omim: 162650 Human

SwissProt: P30990 Human

Unigene: 80962 Hum



Product Picture
Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-Neurotensin Polyclonal Antibody, Unconjugated(SL6631R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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