TEL: +86 571 56623320 EMAIL: [email protected]
Product Name Neurotensin Chinese Name 神经紧张素抗体 Alias Human proneurotensin; NT; NT/N; NTRH; NTS1; Proneuromedin N mRNA; NEUT_HUMAN; Large neuromedin N; Neuromedin N preproprotein; NMN 125; NMN-125; NN; Tail peptide; NN; Neurotensin/neuromedin N. literatures Specific References (1) | SL6631R has been referenced in 1 publications.[IF=1.64] SAKUMOTO, Ryosuke, et al. "Comparison of the global gene expression profiles in the bovine endometrium between summer and autumn." Journal of Reproduction and Development 0 (2015). IHC-P ; Bovine.Research Area Cell biology Neurobiology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species Human, Rat, (predicted: Mouse, Dog, Pig, Cow, Rabbit, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 19kDa Cellular localization cytoplasmic Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Neurotensin: 101-170/170 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active. [provided by RefSeq, Jul 2008].
Cellular localization: Secreted. Cytoplasmic vesicle > secretory vesicle. Packaged within secretory vesicles.
Function:
Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.
Subcellular Location:
Secreted. Cytoplasmic vesicle, secretory vesicle. Note=Packaged within secretory vesicles.
Similarity:
Belongs to the neurotensin family.
SWISS:
P30990
Gene ID:
4922
Database links:Entrez Gene: 4922 Human
Omim: 162650 Human
SwissProt: P30990 Human
Unigene: 80962 Hum
Product Picture Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-Neurotensin Polyclonal Antibody, Unconjugated(SL6631R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
Scan Wechat Qrcode