Product Name	BMP5
Chinese Name	骨形态发生蛋白5抗体
Alias	BMP 5; BMP-5; Bmp5; BMP5_HUMAN; Bone morphogenetic protein 5; MGC34244.
literatures	Specific References  (1)     |     SL6614R has been referenced in 1 publications. [IF=2.24] Wu, Mei, et al. "Expression analysis of BMP2, BMP5, BMP10 in human colon tissues from Hirschsprung disease patients." Int J Clin Exp Pathol 7.2 (2014): 529-536.  IHC-P,WB ;  Human.   PubMed:24551273
Research Area	Cardiovascular  Signal transduction  Stem cells  Growth factors and hormones  Cytoskeleton  Extracellular matrix
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Pig, Horse, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	16kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human BMP5: 317-360/454
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. This protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. This gene is differentially regulated during the formation of various tumors. [provided by RefSeq, Jul 2008]. Function: Induces cartilage and bone formation. Subunit: Homodimer; disulfide-linked (By similarity). Subcellular Location: Secreted. Tissue Specificity: Expressed in the lung and liver. Similarity: Belongs to the TGF-beta family. SWISS: P22003 Gene ID: 653 Database links: Entrez Gene: 653 Human Omim: 112265 Human SwissProt: P22003 Human Unigene: 296648 Human

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