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Product Name STMN3 Chinese Name 原癌基因18家族STMN3蛋白抗体 Alias Sclip; RP23-83A14.1; SCG10-like protein; Scgn10 like protein; Stathmin like 3; STMN3_HUMAN. Research Area Cell biology Neurobiology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Cow, Horse, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 21kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human STMN3: 77-130/180 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail STMN3 belongs to the stathmin/oncoprotein 18 family of microtubule-destabilizing phosphoproteins. It is similar to the SCG10 protein and is involved in signal transduction and regulation of microtubule dynamics.
Function:
Exhibits microtubule-destabilizing activity, which is antagonized by STAT3 (By similarity).
Subunit:
Interacts with STAT3 (By similarity).
Subcellular Location:
Golgi apparatus. Cell projection, growth cone. Cell projection, axon.
Tissue Specificity:
Neuron specific.
Post-translational modifications:
N-terminal palmitoylation promotes specific anchoring to the cytosolic leaflet of Golgi membranes and subsequent vesicular trafficking along dendrites and axons. Neuronal Stathmins are substrates for palmitoyltransferases ZDHHC3, ZDHHC7 and ZDHHC15.
Similarity:
Belongs to the stathmin family.
SWISS:
Q9NZ72
Gene ID:
50861
Database links:Entrez Gene: 50861 Human
Entrez Gene: 20262 Mouse
Omim: 608362 Human
SwissProt: Q9NZ72 Human
SwissProt: O70166 Mouse
Unigene: 639609 Human
Unigene: 2319 Mouse
Unigene: 447659 Mouse
Unigene: 14961 Rat
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