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Rabbit Anti-STMN3 antibody
Rabbit Anti-STMN3 antibody
Sclip; RP23-83A14.1; SCG10-like protein; Scgn10 like protein; Stathmin like 3; STMN3_HUMAN.
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  • NO.:SL6596R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Chicken,Cow,Horse,Sheep,)
    Applications:WB ELISA IHC-P IHC-F IF
    concentration:1mg/ml
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Details

Product Name STMN3
Chinese Name 原癌基因18家族STMN3蛋白抗体
Alias Sclip; RP23-83A14.1; SCG10-like protein; Scgn10 like protein; Stathmin like 3; STMN3_HUMAN.  
Research Area Cell biology  Neurobiology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Chicken, Cow, Horse, Sheep, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 21kDa
Cellular localization cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human STMN3: 77-130/180 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail STMN3 belongs to the stathmin/oncoprotein 18 family of microtubule-destabilizing phosphoproteins. It is similar to the SCG10 protein and is involved in signal transduction and regulation of microtubule dynamics.

Function:
Exhibits microtubule-destabilizing activity, which is antagonized by STAT3 (By similarity).

Subunit:
Interacts with STAT3 (By similarity).

Subcellular Location:
Golgi apparatus. Cell projection, growth cone. Cell projection, axon.

Tissue Specificity:
Neuron specific.

Post-translational modifications:
N-terminal palmitoylation promotes specific anchoring to the cytosolic leaflet of Golgi membranes and subsequent vesicular trafficking along dendrites and axons. Neuronal Stathmins are substrates for palmitoyltransferases ZDHHC3, ZDHHC7 and ZDHHC15.

Similarity:
Belongs to the stathmin family.

SWISS:
Q9NZ72

Gene ID:
50861

Database links:

Entrez Gene: 50861 Human

Entrez Gene: 20262 Mouse

Entrez Gene: 29246 Rat

Omim: 608362 Human

SwissProt: Q9NZ72 Human

SwissProt: O70166 Mouse

SwissProt: Q9JHU6 Rat

Unigene: 639609 Human

Unigene: 2319 Mouse

Unigene: 447659 Mouse

Unigene: 14961 Rat



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