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Rabbit Anti-PAGE1 antibody
Rabbit Anti-PAGE1 antibody
AL5; G antigen family B member 1; GAGE 9; GAGE9; GAGEB1; P antigen family, member 1 (prostate associated); PAGE 1; GAGB1_HUMAN.
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Details

Product Name PAGE1
Chinese Name 前列腺相关P抗原家族成员1抗体
Alias AL5; G antigen family B member 1; GAGE 9; GAGE9; GAGEB1; P antigen family, member 1 (prostate associated); PAGE 1; GAGB1_HUMAN.  
Research Area Tumour  TumourCell biologyMaker  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human, 
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 16kDa
Cellular localization The nucleus cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human PAGE1: 51-146/146 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YRPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. Nothing is presently known about the function of this protein. Alternative splicing results in multiple transcript variants.

Tissue Specificity:
Isolated from prostate cancer cell lines; expression associated with progression to androgen insensitive phenotype. Expressed in normal testis and at lower level in normal placenta.

Similarity:
Belongs to the GAGE family.

SWISS:
O75459

Gene ID:
8712

Database links:

Entrez Gene: 8712 Human

Omim: 300288 Human

SwissProt: O75459 Human

Unigene: 128231 Human



Product Picture
Paraformaldehyde-fixed, paraffin embedded (human cervical carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PAGE1) Polyclonal Antibody, Unconjugated (SL6561R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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