Product Name	NANOGP8
Chinese Name	Stem cells转录因子NANOGP8抗体
Alias	Homeobox protein NANOGP8; MGC119250; NANOG; Nanog homeobox pseudogene 8; NANOGP 8; NANOGP1; NANOGP8; NANP8_HUMAN.
Research Area	Tumour  Cell biology  immunology  Chromatin and nuclear signals  transcriptional regulatory factor  TumourCell biologyMaker
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Chicken, Dog, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	34kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human NANOGP8: 101-200/305
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This locus is a processed pseudogene of the transcription factor NANOG. NANOG plays a central role in regulating self-renewal in pluripotent stem cells and tumor cells. This pseudogene contains an intact open reading frame that could potentially encode a protein similar to NANOG. Although there is no evidence of transcription from this pseudogene, RT-PCR studies suggest that NANOGP8 may be expressed in some cancer cell lines. In vitro studies using a recombinant NANOGP8 protein have shown that the protein localizes to the nucleus and can promote cell proliferation, similar to NANOG. [provided by RefSeq, Sep 2009] Function: May act as a transcription regulator. When overexpressed, promotes entry of cells into S phase and cell proliferation. Subcellular Location: Nucleus. Tissue Specificity: Expressed in osteosarcoma cancer cell line (at protein level). breast and urinary bladder tissues, and also osteosarcoma, hepatoma, and breast adenocarcinoma cancer cell lines. Similarity: Belongs to the Nanog homeobox family. Contains 1 homeobox DNA-binding domain. SWISS: Q6NSW7 Gene ID: 388112 Database links: Entrez Gene: 388112 Human SwissProt: Q6NSW7 Human
Product Picture	Sample: Jurkat(Human) Cell Lysate at 30 ug Primary: Anti-NANOGP8 (SL6552R) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 34 kD Observed band size: 34 kD

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